Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0312734
PubChem CID
Molecular Formula
C9H15N5O
Molecular Weight
209.253 g/mol
Synonyms/Alias
[minoxidil; 38304-91-5; Rogaine; Loniten; Minoximen; Regaine; Theroxidil; Alopexil; Alostil; Tricoxidil; Lonolox; Normoxidil; Prexidil; Minodyl; Pierminox; RiUP; Mintop; 2;4-Pyrimidinediamine; 6-(1-pi...
InChI Key
ZIMGGGWCDYVHOY-UHFFFAOYSA-N
InChI
InChI=1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2
IUPAC Name
3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine
CAS Number
38304-91-5

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

30 31 0 0 0 0 0 0 0 0999 V2000
3.7382 -0.1469 -0.2646 C 0 0 0 0 0 0 0 0 0 0 0 0
2.8217 -0.8213 -1.2981 C 0 0 0 0 0 0 0 0 0 0 0 0
1.4289 -1.110...

Experimental Data

Activity Data

Target Ion Channel
Inwardly rectifying subfamily J member 13
Uniprot Accession Number
Function
Inactive
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
No effect

Experimental Conditions

pH
pH 7.4
Holding Potential
−40 mV mV
Temperature
25 °C
Test Method
Patch-clamping
Test Species
Guinea pig

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
15
Rotatable Bonds
1
logP
0.1724
Complexity
55.7426
TPSA (Ų)
91.16
H-Bond Donors
3
H-Bond Acceptors
6
Ring Count
2
New Search